Fig. 2
From: A cilia-bound unconventional secretory pathway for Drosophila odorant receptors
Or22a soma to cilia transport is enhanced where conventional ER to Golgi trafficking is disrupted. A A simplified diagram of the conventional protein trafficking process. Proteins of the COPII anterograde transport machinery are listed. Figure produced on BioRender.com. B The knockdown of COPII genes in OSNs did not abrogate Or22a puncta at either soma (blue arrows) or dendrite (yellow arrows). For many, cilia Or22a levels were instead intensified (orange arrows), an indication of heightened cilia-bound traffic. C Quantitative analyses for Or22a puncta frequency across a population of Or22a OSNs. D Quantitative analyses for Or22a intensity ratios in cilia vs soma. For control, n = 12; for other genotypes, n = 6, where n is the total number of antennas analyzed; error bars represent mean SEM. One-way ANOVA with multiple comparison test and Dunnett’s correction was applied for statistical analysis