Table 5 Amino acid attributes and division of the amino acids to groups²⁴

Charge

Neutral

Negatively charged

Positively charged

A, C, F, G, H, I, L, M, N, P, Q, S, T, V, W, Y

D, E

K, R

Hydrophobicity

Hydrophobicity

Neutral

Polar

C, F, I, L, M, V, W

A, G, H, P, S, T, Y

D, E, K, N, Q, R

Normalized van der Waals volume

0–2.78

2.95–4.0

4.03–8.08

A, C, D, G, P, S, T

E, I, L, N, Q, V

F, H, K, M, R, W, Y

Polarity

4.9–6.2

8.0–9.2

10.4–13.0

C, F, I, L, M, V, W, Y

A, G, P, S, T

D, E, H, K, N, Q, R

Polarizability

0–0.108

0.128–0.186

0.219–0.409

A, D, G, S, T

C, E, I, L, N, P, Q, V

F, H, K, M, R, W, Y

Secondary structure

Coil

Helix

Strand

D, G, N, P, S

A, E, H, K, L, M, Q, R

C, F, I, T, V, W, Y

Solvent accessibility

Buried

Intermediate

Exposed

A, C, F, G, I, L, V, W

H, M, P, S, T, Y

D, E, K, N, R, Q