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Fig. 10 | BMC Biology

Fig. 10

From: A network of transcription factors in complex with a regulating cell cycle cyclin orchestrates fungal oxidative stress responses

Fig. 10

The network consisting of three TFs, BbOsrR1, 2, and 3, and cyclin BbClp1 orchestrates B. bassiana development, oxidative stress responses, and virulence. BbOsrR1 negatively regulates BbOsrR2 and BbClp1 transcription via targeting their promoters. BbClp1, BbOsrR2, and BbOsrR3 forms a regulatory complex, in which BbClp1 directly interacts with BbOsrR2 but not with BbOsrR3, with BbClp1 partially regulating BbOsrR2 phosphorylation. The network finely regulates fungal conidiation and germination, oxidative stress responses, and virulence via control of Fus3-MAPK pathway, fungal development, antioxidation and detoxification, and virulence-involved genes

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BMC Biology

ISSN: 1741-7007

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