Involvement of Plasmodium falciparum protein kinase CK2 in the chromatin assembly pathway

Table 1 Potential interactors in the nucleosome assembly and regulation pathway.^a

Protein^b	PlasmoDB	PfCK2β1HA (3D7/tagged)^c	PfCK2β2HA (3D7/tagged)^c
PfCK2α	MAL13P1.237	1/161	1/188
PfCK2β1	PF11_0048	1/31	1/24
PfCK2β2	PF13_0232	0/37	0/33
PfNapL	PFL0185c	0/3	0/3
PfNapS	PFI0930c	0/4	0/2
Histone H2A	PFF0860c	0/35	X^d
Histone H2A variant	PFC0920w	2/25	2/6
Histone H2B	PF11_0062	2/11	2/3
Histone H2B variant	PF07_0054	0/4	X
Histone H3	PFF0510w	3/13	3/5
Hhistone H4	PF11_0061	2/11	X
High mobility group protein	MAL8P1.72	0/2	X
Chromodomain helicase DNA-binding protein	PF10_0232	0/3	0/6
Smarca-related protein	PFF1185w	0/8	0/2
Structure-specific recognition protein	PF14_0393	0/2	X
PfAlba1	PF08_0074	6/12	6/7
PfrAlba2	MAL13P1.233	0/2	X
PfAlba3	MAL13P1.237	2/9	2/4
PfAlba4	PF10_0063	2/6	X

^aProteins found in the HA-PfCK2β1 and HA-PfCK2β2 immunoprecipitates, which are part of the 'nucleosome assembly and regulation pathway' described in the MPMP website, or have been implicated in chromatin dynamics.
^bData are taken from Additional Tables A2 and A3, which display the entire list of recovered proteins.
^cFor each column, the unweighted spectrum count is given first for the immunoprecipitate obtained from 3D7 wild-type parasite, and then from the transgenic parasites expressing HA-tagged PfCK2β1or PfCK2β2.
^dX signifies that the protein was not found in the immunoprecipitate.

ISSN: 1741-7007