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Figure 1 | BMC Biology

Figure 1

From: RNAi in the regulation of mammalian viral infections

Figure 1

miRNA-, siRNA-, piRNA-RISC complexes effect complementarity-driven silencing of targeted mRNAs. Small miRNAs, siRNAs, or piRNAs (red) serve as guide sequences within the RNA-induced silencing complex (RISC) to capture target mRNA via incomplete (miRNA) or complete (siRNA, piRNA) base-pairing. The expression of the targeted mRNA is silenced either by RNA degradation or by inhibition of translation.

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BMC Biology

ISSN: 1741-7007

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