Natural genetic variation determines susceptibility to aggregation or toxicity in a C. elegansmodel for polyglutamine disease

Table 1 Lifespan analysis

Name	Number	Restricted mean			Age in days at percentage mortality					95% median CI
		Days	SEM	95% CI	25%	50%	75%	90%	100%
daf-16	119	16.17	0.51	15.16 to 17.18	13	15	19	22	31	14 to 15
age-1	107	29.57	1.62	26.39 to 32.75	17	27	42	50	53	22 to 30
Bristol	100	19.92	0.84	18.26 to 21.57	13	21	25	29	31	19 to 21
DR1350	123	22.75	0.85	21.09 to 24.41	21	23	26	28	34	21 to 25
Q40Bristol	120	14.89	0.46	13.98 to 15.80	11	15	17	20	28	15 to 15
Q40DR1350	102	18.32	1.06	16.24 to 20.39	12	18	25	26	28	15 to 22
Q40DR1350	40	16.53	0.99	14.59 to 18.48	12	17	22	23	24	15 to 19
RIL 2	100	13.6	0.54	12.54 to 14.67	12	13	16	19	21	13 to 14
RIL 2	102	13.49	0.49	12.53 to 14.45	11	13	17	18	26	12 to 12
RIL 10	117	17.33	0.51	16.33 to 18.34	15	17	20	23	28	15 to 17
RIL 12(2)	100	13.5	0.59	12.35 to 14.64	10	14	18	19	23	12 to 14
RIL 12(2)	116	14.66	0.34	13.99 to 15.33	12	15	17	19	26	14 to 14
RIL 15	70	15.69	0.91	13.90 to 17.48	12	15	18	21	26	14 to 17
RIL 15	111	14.81	0.68	13.49 to 16.14	12	15	17	21	33	12 to 14
RIL 16	91	18.6	1.11	16.43 to 20.76	14	19	23	25	26	15 to 22
RIL 16	115	18.65	0.99	16.70 to 20.60	15	17	23	28	27	15 to 19

ISSN: 1741-7007