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Figure 6 | BMC Biology

Figure 6

From: The roles of calcium signaling and ERK1/2 phosphorylation in a Pax6 +/-mouse model of epithelial wound-healing delay

Figure 6

EGF addition corrects the wound response in mutants. (A)Priming Pax6 +/- cultures 90 s prior to wounding with 10 ng/ml EGF induced a significantly more intense Ca2+ wave that was comparable to Pax6 +/+ cultures (p = 0.667). (B) The initial rate of healing in EGF-treated Pax6 +/- cultures was restored to wild-type levels, and significantly higher than in control Pax6 +/- cultures (*, p < 0.001).

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