Figure 5
From: Modulation of Aβ42low-n oligomerization using a novel yeast reporter system
Deletion of HSP104 exacerbates the translation termination defect of AβMRF. Equal numbers of sup35Δ yeast containing (WT) or lacking (Δ) HSP104 and expressing AβMRF or Aβm2MRF were grown on complex medium, or synthetic medium supplemented (+Ade) or not (-Ade) with adenine. Deletion of HSP104 stimulated growth of AβMRF-expressing cells on -Ade, while having no effect on yeast grown on +Ade medium.