Skip to main content

Table 1 Summary of genotype association analyses with BSE status

From: A major genetic component of BSE susceptibility

 

23-bp indel

 

12-bp indel

 
 

Frequency of Genotypes

 

Frequency of Genotypes

 

UK Holstein

Casesa

(n)

Controlsa

(n)

P-Valuec

Casesa

(n)

Controlsa

(n)

P-Valuec

del/del

55.4

(201)

46.4

(128)

2.4 × 10-2

49.4

(173)

37.0

(100)

2.1 × 10-3

del/ins

41.0

(149)

48.9

(135)

4.7 × 10-2

45.4

(159)

51.9

(140)

1.1 × 10-1

ins/ins

3.6

(13)

4.7

(13)

4.7 × 10-1

5.1

(18)

11.1

(30)

5.8 × 10-3

German Holstein b

          

del/del

45.7

(58)

38.0b

(119)b

1.4 × 10-1

40.0

(50)

28.2b

(87)b

1.6 × 10-2

del/ins

46.5

(59)

47.3b

(148)b

8.8 × 10-1

45.6

(57)

49.8b

(154)b

4.2 × 10-1

ins/ins

7.9

(10)

14.7b

(46)b

5.2 × 10-2

14.4

(18)

22.0b

(68)b

7.2 × 10-2

German Brown

          

del/del

20.9

(9)

13.8

(12)

2.9 × 10-1

7.0

(3)

3.3

(3)

3.4 × 10-1

del/ins

65.1

(28)

41.4

(36)

1.1 × 10-2

51.2

(22)

22.2

(20)

7.8 × 10-4

ins/ins

14.0

(6)

44.8

(39)

5.0 × 10-4

41.9

(18)

74.4

(67)

2.5 × 10-4

German Fleckvieh

          

del/del

53.8

(57)

46.3

(63)

2.5 × 10-1

45.3

(48)

39.4

(54)

3.6 × 10-1

del/ins

39.6

(42)

43.4

(59)

5.6 × 10-1

46.2

(49)

45.3

(62)

8.8 × 10-1

ins/ins

6.6

(7)

10.3

(14)

3.1 × 10-1

8.5

(9)

15.3

(21)

1.1 × 10-1

  1. a Represents frequency (%) of genotypes; (n) indicates the number of genotypes.
  2. b Control consists of half-sibs (see Additional File 1: Inferring allele, genotype, haplotype and diplotype frequencies from half-sibs).
  3. c P-values of χ2-test against the both remaining genotypes