Table 3 Summary of haplotype association analyses with BSE status
Frequency of Haplotypes | Logistic Regression Analysis | |||||||
|---|---|---|---|---|---|---|---|---|
UK Holstein | Casesa | (n) | Controlsa | (n) | P-Valuec | ORd | P-Value 23ins-12inse | P-Value 23del-12insf |
23ins-12ins | 24.2 | (171) | 29.1 | (159) | 5.1 × 10-2 | 1 | 6.6 × 10-2 | |
23del-12ins | 4.1 | (29) | 8.1 | (44) | 3.1 × 10-3 | 0.62 | 6.6 × 10-2 | |
23del-12del | 71.7 | (506) | 62.8 | (343) | 8.9 × 10-4 | 1.37 | 1.6 × 10-2 | 1.3 × 10-3 |
German Holstein | ||||||||
23ins-12ins | 30.2 | (77) | 39.1b | (232) | 1.4 × 10-2 | 1 | 8.1 × 10-1 | |
23del-12ins | 7.2 | (17) | 9.1b | (56) | 3.9 × 10-1 | 0.93 | 8.1 × 10-1 | |
23del-12del | 62.2 | (162) | 51.3b | (327) | 7.5 × 10-3 | 1.49 | 1.4 × 10-2 | 1.1 × 10-1 |
German Brown | ||||||||
23ins-12ins | 45.0 | (39) | 66.1 | (119) | 1.3 × 10-3 | 1 | 1.8 × 10-1 | |
23del-12ins | 22.5 | (18) | 19.4 | (35) | 5.7 × 10-1 | 1.58 | 1.8 × 10-1 | |
23del-12del | 32.5 | (27) | 14.4 | (26) | 7.8 × 10-4 | 3.14 | 5.4 × 10-4 | 8.4 × 10-2 |
German Fleckvieh | ||||||||
23ins-12ins | 26.8 | (58) | 32.6 | (90) | 1.7 × 10-1 | 1 | 7.5 × 10-1 | |
23del-12ins | 5.1 | (11) | 5.4 | (15) | 8.7 × 10-1 | 1.15 | 7.5 × 10-1 | |
23del-12del | 68.1 | (147) | 62.0 | (171) | 1.7 × 10-1 | 1.33 | 1.5 × 10-1 | 7.2 × 10-1 |
Combined | ||||||||
23ins-12ins | 1 | 5.0 × 10-1 | ||||||
23del-12ins | 0.90 | 5.0 × 10-1 | ||||||
23del-12del | 1.50 | 3.7 × 10-6 | 9.6 × 10-4 | |||||