Figure 4

Correlation between evolutionary rate and degree and expression level. (A) The boxplots of Kendall's rank correlation coefficient (red) show a weak anti-correlation between evolutionary rate and degree, which increases with subnet size. The corresponding partial correlation coefficients (blue) indicate a weaker anti-correlation when protein expression level is controlled for. (B) Correlation coefficients (red) between evolutionary rate and protein expression level and partial correlation coefficients (blue) which account for differences in protein degree. The anti-correlations found here are stronger than those shown in part A of this figure. The horizontal dot-dashed lines represent the correlation coefficients of the full network.