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Table 4 Validation of gene expression changes in the E18.5 Pygo1/Pygo2 null kidneys normalized to E18.5 wild-type kidneys.

From: Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development

Gene symbol

Microarray fold change

QPCR fold change (SD)

Validation

Aldh1a7

- 2.2

1.1 (0.11)

No

Col8a1

2.1

2.9 (0.78)

Yes

Csrp1

- 7.1

1.2 (0.02)

No

Klk5

2.8

5.8 (0.74)

Yes

Pygo2

- 3.9

- 3.7 (0.04)

Yes

Picalm

3.1

2.2 (0.24)

Yes

Ren2

2.2

6.1 (0.36)

Yes

Tia1

6.6 and 2.3

Amplification not detected in wild-type samples

Yes