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Table 1 Percentage amino acid identity. Pairwise analysis of each FIGLER domain was performed using the Megalign CLUSTALW method algorithm, with FIGLER 1 serving as the index of comparison. Percent amino acid identities are indicated and aligned in relation to the FIGLER 1 domains. The identity percentage scoring employed here did not penalize for shortened cytoplasmic tails or the presence of < 8 LRRs.

From: A conserved gene family encodes transmembrane proteins with fibronectin, immunoglobulin and leucine-rich repeat domains (FIGLER)

Amino acid identity (%)

FIGLER

2

3

4

5

6

7

8

9

LRR

53.1

33.6

28.1

32.1

62.2

35.0

56.6

27.9

Ig C2

55.4

36.9

31.8

38.5

64.6

41.5

52.3

32.9

FNIII

48.8

13.4

12.2

17.1

47.6

15.9

54.4

13.0

IC

39.2

6.8

13.2

13.5

29.7

17.6

36.5

11.4

EC

36.3

25.8

19.0

25.6

53.7

29.0

48.4

24.5

Overall

33.0

22.5

20.8

24.4

47.3

25.3

43.6

22.6