Skip to main content
Figure 2 | BMC Biology

Figure 2

From: Spatial chemical conservation of hot spot interactions in protein-protein complexes

Figure 2

Alignment examples. (A) Alignment of 3 RNase-inhibitor PPIs. The Angiogenin is yellow (1a4yB) and the Rnase Sa (1ay7A) and barnase (1brsA) are dark and light orange. The Leucine-rich RI (1a4yA) is in magenta while the barstars (1ay7B,1brsD) are blue and purple. The rightmost figure shows the conserved interactions with the identities of the amino acids that create them in the corresponding complexes (1a4y:1ay7:1brs). The pseudocenters are represented as in Figure 1A, except the aromatic properties which are cyan. The RIs are light purple and the RNases are monochrome. (B) Alignment of 6 PPIs of E9-Im9 (1bxiAB, 1emvAB, 1fr2AB) and E7-Im7(1mz8AB, 1ujzAB, 1fr2AB). The E9 are cyan and the E7 are blue. The Im9 and Im7 are yellow and red respectively. The right figure details the 7 conserved interactions labeled by the amino acids of 1bxiAB.

Back to article page