Figure 7
From: Connexin channels and phospholipids: association and modulation
Connexin channel activity as a function of mol% cholesterol content. Channel activity of homomeric Cx26 (squares) and Cx32 (circles) channels was assessed by transport-specific fractionation (as in Figure 6). Channel activity was normalized to activity in zero cholesterol (PC:0.02DOPE-fluorophore, mol:mol). Data points are at 8, 16, 23, 31 and 47 mol% cholesterol. CHOL = cholesterol; PC = phosphatidylcholine. n equals three to six trials per data point.