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Figure 7 | BMC Biology

Figure 7

From: The nucleotide addition cycle of RNA polymerase is controlled by two molecular hinges in the Bridge Helix domain

Figure 7

Evolutionary positions of bacterial species with proline-containing Bridge Helices. The evolutionary relationship between three bacterial species with proline-containing Bridge Helices is shown on a rooted phylogenetic tree calculated using maximum-likelihood methods from a concatenation of representative protein sequences [63]. The three species occupy widely divergent branches, strongly suggesting that the proline substitutions evolved independently, rather than were derived from a recently shared ancestor.

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