Table 4 Significance of the over/under-representation of orthologues of Saccharomyces cerevisiae haploinsufficient (HI) genes on the mating-type chromosomes of ascomycetes and the sex chromosomes of animals
From: Haploinsufficiency and the sex chromosomes from yeasts to humans
Organism | Predominant lifecycle phase | Mating-type or sex determination system | Orthologues of Saccharomyces cerevisiae HI genes on the mating-type/sex chromosome(s) |
|---|---|---|---|
| Â | Â | Â | P value for over-representation |
Saccharomyces cerevisiae | Diploid | Bipolar sexuality | <10-50 |
Saccharomyces castellii | Diploid | Bipolar sexuality | <10-10 |
Candida glabrata | Diploid | Bipolar sexuality | <10-10 |
Saccharomyces kluyveri | Diploid | Bipolar sexuality | <10-12 |
Kluyveromyces lactis | Haploid | Bipolar sexuality | <10-19 |
Ashbya gossypii | Haploid | Bipolar sexuality | 0.02 |
Candida albicans | Diploid | Asexual | 0.8 |
Candida dubliniensis | Diploid | Asexual | 0.6 |
Debaryomyces hansenii | Haploid | Bipolar sexuality | 0.05 |
Yarrowia lipolytica | Haploid | Bipolar sexuality | 0.002 |
| Â | Â | Â | P value for under-representation |
Homo sapiens | Diploid | X/Y | 0.02 |
Pan troglodytes | Diploid | X/Y | 0.04 |
Mus musculus | Diploid | X/Y | 0.05 |
Rattus norvegicus | Diploid | X/Y | 0.04 |
Equus caballus | Diploid | X/Y | 0.01 |
Bos taurus | Diploid | X/Y | 0.3 |
Canis familiaris | Diploid | X/Y | 0.02 |
Gallus gallus | Diploid | Z/W | 0.3 |
Drosophila melanogaster | Diploid | X/Y | 0.9 |
Caenorhabditis elegans | Diploid | X/0 | 0.02 |