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Figure 8 | BMC Biology

Figure 8

From: Clustered ChIP-Seq-defined transcription factor binding sites and histone modifications map distinct classes of regulatory elements

Figure 8

Transcript and enhancer clusters mapping within and outside annotated genes and correlation with actual transcripts. (A) Number of transcript and enhancer clusters mapping within and outside annotated genes and promoters in both cell lines. (B) Number of transcript clusters mapping to genes with high, low/medium and zero expression in both cell lines as measured by high throughput RNA-sequencing (RNA-seq). (C) Number of enhancer clusters mapping to genes with high, low/medium and zero expression in both cell lines as measured by RNA-Seq. Methylation of lysine 4 on histone H3 (H3K4me) is a more specific marker of transcription factor clusters than is open chromatin (OCR)

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