Figure 2

Conservation of editing responses across Drosophilidae . (A) Editing at sites 2 to 4 in the synaptotagmin-1 transcript. (B) Editing at sites 1 to 3 in the paralytic transcript. (C) Editing at sites 6 and 7 in the shab transcript. The slopes of the species-specific editing response curves, rather than the absolute editing, were statistically compared to those of D. melanogaster (black) for each site. P <0.0001: **, P <0.05: *. Bars in A through C represent standard error. (D) Phylogeny of the five Drosophilidae species used in this study. D. ananassae represents an outgroup species. Colors are as in A through C. Branch lengths represent evolutionary time, based on Tamura et al. [30].