Skip to main content
Figure 8 | BMC Biology

Figure 8

From: The development and maintenance of the mononuclear phagocyte system of the chick is controlled by signals from the macrophage colony-stimulating factor receptor

Figure 8

The effect of chicken CSF1-Fc in macrophage concentration in tissues detected by whole mount imaging of MacRed chick. Hatchlings were dosed subcutaneously with 50 μg chicken CSF1-Fc or PBS on hatch day (day 0), day 1, day 2 and day 3, then sacrificed 24 hours after the final injection. Tissues were collected quickly following the sacrifice of the chicks, and put in ice-cold PBS for imaging under UV light using a red fluorescence filter for the same exposure time. (A) Skin biopsy, 40× magnification. (B) Inner surface of the rectum, split open, 80× magnification. (C) Cecum, 12.5× magnification. PBS, phosphate-buffered saline.

Back to article page