Fig. 5

ARS capture and fitnesses. a Distribution of distances between ARSs and replication origins. The observed distribution is shown in blue. The simulation of 1,000 independent experiments is shown in gray (see text). The dotted red line corresponds to the 3-kb distance limit that was chosen to define bona fide origins. b Coverage of each ARS at G50 (y axis) as compared to G0 (x axis). The dotted red line corresponds to a coverage ratio 1/1. ARSs with the highest G50 coverage are labeled. c Same as b, but for G100 coverage of each ARS (y axis), as compared to G50 coverage (x axis). ARS autonomously replicating sequence