Skip to main content
Fig. 3 | BMC Biology

Fig. 3

From: Systems-level organization of yeast methylotrophic lifestyle

Fig. 3

Regeneration of pentose phosphates. Left: Methanol assimilation through the xylulose-monophosphate cycle: proposed rearrangements employing an alternative XYL5P forming pathway via S1,7BP. The net reaction of methanol assimilation is the formation of one GAP molecule from three methanol molecules. Right: Rearrangement reactions of the Calvin cycle. Regeneration of ribulose-1,5-bisphosphate (Rul-1,5-BP) needed for CO2 fixation in chloroplasts of plants via S1,7BP. For simplicity, the initial reaction steps after carbon fixation are condensed. The enzyme RuBisCO catalyzes the fixation of CO2 to Rul-1,5-BP, which yields two 3-phosphoglycerate molecules, which are phosphorylated to 1,3-bisphosphoglycerate by phosphoglycerate kinase, and then reduced to GAP by glyceraldehyde 3-phosphate dehydrogenase. Involved metabolites are in oval signs, genes/proteins are shown in rectangular signs. The colors of the individual metabolites serve for better readability of the figure, that is, chemically related compounds share the same color. The regulation pattern and the cellular localization of the proteins is given in Table 2

Back to article page