Fig. 7

Participation of Nipi gene products in oxidative phosphorylation. The upper part of the figure shows a KEGG-derived schematic representation of the successive complexes that make up the mitochondrial electron transport chain (KEGG pathway cel00190) on which the complexes that include any proteins corresponding to Nipi clone targets are highlighted. For any targets of the 297 clones that did not provoke a strong developmental phenotype, the E.C. name for each complex is boxed in red with red text; for the targets of the remaining 63 clones (Table 2; Additional file 5: Table S5) there is one additional complex (E.C. 1.3.5.1, succinate dehydrogenase), boxed in red with black text. The lower part of the figure shows the individual protein components of the different complexes, annotated as above. Proteins for which there is no KEGG-assigned ortholog in C. elegans are uncolored. A full explanation of the symbols can be found at http://www.kegg.jp/kegg/document/help_pathway.html