From: A quantitative genome-wide RNAi screen in C. elegans for antifungal innate immunity genes
Gene/sequence name | Brief description |
---|---|
dcar-1 | GPCR receptor; activated by HPLA [20] |
elo-2 | Palmitic acid elongase; ELO-2 is required with ELO-1 for 20-carbon PUFA production |
frpr-11 | GPCR of the FMRFamide Peptide Receptor family; unlike dcar-1, acts downstream of gpa-12 and blocks osmotic induction of nlp-29 [20] |
ins-6 | Predicted type-beta insulin-like peptide |
mltn-12 | MLt-TeN (mlt-10) related; MLT-10 is a nematode-specific protein required for ecdysis |
nas-37 | Astacin-class metalloprotease required for ecdysis; N-terminal signal sequence followed by an Astacin protease domain and three protein-binding domains (EGF-like, CUB, and thrombospondin) |
srsx-25 | GPCR of the serpentine receptor class SX |
srv-21 | GPCR of the serpentine receptor class V; unlike dcar-1, acts downstream of gpa-12 and blocks osmotic induction of nlp-29 [20] |
sta-2 | STAT family of transcription factor [7] |
F56A8.5 | Protein containing an F-box |
K08C9.5 | Protein containing an F-box |
C33D9.3 | Nematode-specific |
F27C8.2a | Nematode-specific |
F27C8.3a | Nematode-specific |
F34H10.1 | Ubiquitin/40S ribosomal protein S27a fusion protein |
K08C9.7 | Ubiquitin/40S ribosomal protein S27a fusion protein |
R186.8 | 39S ribosomal protein L33, mitochondrial |
T08D2.2b | Similar to C-terminal half of UDP-N-acetylglucosamine-dolichyl-phosphate N-acetylglucosaminephosphotransferase |
T08D2.6b | YIPF4-like; YIPF4, poorly characterized membrane spanning protein; in yeast, interacts with Rab GTPases |
Y60A3A.19 | YIPF4-like.;YIPF4, poorly characterized membrane spanning protein; in yeast, interacts with Rab GTPases |
C42C1.3 | Nematode-specific |
F35F10.14 | Nematode-specific |
F41H8.1c | Nematode-specific domain: GPCR of the serpentine receptor class BC |
K09C6.6c | Nematode-specific domain: GPCR of the serpentine receptor class BC |
K09C6.10c | Nematode-specific |
F42C5.9 | Actin |
F45E4.5 | Nematode-specific |
F49H12.5 | Thioredoxin domain-containing protein 12-like |
F52C6.13 | Nematode-specific |
tsen-54 | N-terminal half similar to that of tRNA-splicing endonuclease subunit Sen54 |
Y39G10AR.7 | Nematode-specific |
Y51H7BR.7 | Contains Spec3 domain, like Drosophila Stumbled |
Y67D8C.22 | Clarin-like |