Skip to main content

Table 2 Candidate interactors identified

From: A tissue-specific protein purification approach in Caenorhabditis elegans identifies novel interaction partners of DLG-1/Discs large

Bait

Interactor

SAINT confidence scores

Description

Ubiquitous

Intestine

Seam/hyp7

Neuron

CDC-42

CDC-42

1.00

1.00

1.00

-

RHO GTPase

DLG-1

VIT-5

0.60

0.00

1.00

0.33

Vitellogenin

DLG-1

UNC-87

1.00

0.54

0.36

0.61

Maintains structure of myofilaments

DLG-1

DLG-1

1.00

1.00

1.00

1.00

Discs large

DLG-1

VIT-6

0.65

0.00

0.99

0.33

Vitellogenin

DLG-1

ATAD-3

0.99

0.46

0.71

0.49

Mitochondrial protein ATAD3

DLG-1

DIM-1

0.22

0.00

0.04

0.98

Uncharacterized

DLG-1

C39H7.4

0.65

-

0.98

0.33

Uncharacterized

DLG-1

COR-1

0.97

0.33

0.33

0.33

Coronin

DLG-1

LEC-1

0.96

0.06

0.84

0.62

Tandem-repeat type galectin

DLG-1

MAPH-1.1

0.00

-

-

0.93

MAP1 homolog

DLG-1

IFB-2

0.66

0.00

0.90

0.93

Intermediate filament protein

DLG-1

F49H12.5

0.56

0.03

0.01

0.93

Thioredoxin domain containing 12

DLG-1

LARP-1

0.00

0.00

0.21

0.92

La-related protein

DLG-1

IFC-2

0.00

0.00

0.91

0.33

Intermediate filament protein

DLG-1

LEC-2

0.90

0.00

0.91

-

Tandem-repeat type galectin

DLG-1

R09H10.5

0.89

0.25

0.91

0.32

Uncharacterized

DLG-1

MUP-2

0.90

0.63

0.28

0.66

Muscle contractile protein troponin T

DLG-1

ATN-1

-

0.31

0.90

-

Alpha-actinin homolog

DLG-1

GPD-2

0.83

0.01

0.89

0.39

GAPDH

DLG-1

QARS-1

0.00

0.00

0.88

0.39

Glutaminyl (Q) tRNA synthetase

DLG-1

VARS-2

0.00

-

0.00

0.88

Valyl-tRNA synthetase

DLG-1

NMT-1

0.00

-

0.58

0.87

N-myristoyl transferase

DLG-1

MRG-1

0.00

0.00

0.12

0.87

Homolog of MRG15

DLG-1

EPS-8

0.85

0.05

0.82

0.66

Cell signaling adaptor protein

DLG-1

T25F10.6

0.83

0.64

0.22

0.33

Calponin

DLG-1

LEC-4

0.65

-

0.81

0.33

Tandem-repeat type galectin

LET-413

LET-413

1.00

0.86

1.00

-

Scribble

LET-413

B0303.3

0.82

0.00

-

-

Beta-ketothiolase

LET-413

QARS-1

0.82

0.01

-

-

Glutaminyl (Q) tRNA synthetase

LGL-1

LGL-1

1.00

1.00

1.00

-

Lethal giant larvae (Lgl)

LGL-1

PAR-6

0.99

1.00

0.98

-

Par-6

LGL-1

PKC-3

0.98

0.97

0.91

-

Atypical protein kinase C

LGL-1

QARS-1

0.82

0.00

0.00

-

Glutaminyl (Q) tRNA synthetase

  1. Shown are putative interactors identified with a SAINT confidence score >0.8 in at least one of the four tissues examined. Ribosomal proteins are not shown. An expanded copy of this table including spectra counts is shown in Additional file 5: Table S2