Table 2 Minimum inhibitory concentrations (μg/mL) for E. coli containing a plasmid encoding N-terminally His-tagged wild-type MCR-1 and MCR-1 T285A
From: Structure of the catalytic domain of the colistin resistance enzyme MCR-1
E. coli + | Colistin | Polymyxin B |
|---|---|---|
pET28a (empty vector) | 0.032 | 0.032 |
mcr-1 pET28a | 8.0 | 6.0 |
mcr-1 T285A pET28a | 0.125 | 0.092 |