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Table 2 List of conserved endocrine-enriched transcription factors

From: Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes

Gene

Endocrine

Acinar

Duct

Conservation

runx1t1

535

2

7

ZHM

isl1

8613

41

76

ZHM

myt1la

96

0

4

ZHM

fev

5884

128

44

ZHM

neurod1

28467

260

300

ZHM

ascl1a

86

0

1

ZHM

rfx6

1517

26

5

ZHM

pax6b

8059

47

23

ZHM

insm1b

1200

6

39

ZHM

npas4a

4497

11

114

ZHM

arxa

1697

38

1

ZHM

myt1a

532

0

17

ZHM

insm1a

3419

10

248

ZHM

lmo1

1425

4

1

ZHM

etv1

284

0

0

ZHM

esrrga

159

8

2

ZM

rfx2

1590

46

253

ZM

sim1a

164

2

1

ZM

mnx1

1368

144

3

ZM

cdx4

144

0

16

ZM

bhlhe41

2984

712

640

ZM

lmx1bb

145

2

18

ZM

znf516

219

3

31

ZM

esr1

1701

10

59

ZH

tbx2b

1246

7

8

ZH

pgr

399

4

15

ZH

nkx3.2

293

0

26

ZH

nr0b1

284

14

8

ZH

sox11b

49

1

10

ZH

  1. Transcription factors enriched in endocrine cells in zebrafish, human and/or mouse. The level of expression in endocrine, acinar, and ductal cells is shown for each gene in the second, third, and fourth column, respectively. The degree of expression pattern conservation is shown in the last column as ZHM: endocrine-enriched in zebrafish, human, and mouse; ZM: endocrine-enriched in zebrafish and mouse; ZH: endocrine-enriched in zebrafish and human