Fig. 1.
From: Q&A: What are pathogens, and what have they done to and for us?
Age of emergence of significant infectious diseases impacting on human populations. The time of emergence for the various major diseases is based on a synthesis of published research. When known with some confidence, point estimates are provided for each disease together with error bars depicting uncertainty in the inferred estimates. Orange error bars depict higher uncertainty compared to red. The black trend line plots an increase in human population size through time (x axis) in the order of billions of people (y axis). Key events in human history are highlighted and annotated at the top. Main references used were: smallpox [27]; influenza [28]; HIV [29]; tuberculosis [30,31,32,33]; P. falciparum malaria [34, 35]; hepatitis B [36]; measles [37]; plague [38, 39]