From: An elevated plus-maze in mixed reality for studying human anxiety-related behavior
Measures | Lorazepam | Placebo | Yohimbine | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Mean | ± SE | Min | Max | Mean | ± SE | Min | Max | Mean | ± SE | Min | Max | |
Latency open arm exploration (s) | 42.1 | 9.5 | 5.3 | 113.8 | 92.9 | 25.8 | 9.8 | 300 | 148.9 | 34.4 | 4.2 | 300 |
Latency open arm end exploration (s) | 133.6 | 26.6 | 15.5 | 300 | 177.1 | 28.7 | 17.6 | 300 | 193.4 | 31.7 | 11.5 | 300 |
Time on open arms (s) | 131.3 | 9.6 | 52.8 | 187.4 | 97.8 | 15.5 | 0 | 195.0 | 58.1 | 14.6 | 0 | 146.7 |
Time on open arms (%) | 43.8 | 3.2 | 17.6 | 62.5 | 32.6 | 5.2 | 0 | 65.0 | 19.4 | 4.9 | 0 | 48.9 |
Time on closed arms (s) | 46.1 | 5.6 | 10.8 | 105.3 | 39.1 | 9.5 | 0 | 165.3 | 53.3 | 15.4 | 0 | 218.2 |
Time in center (s) | 122.1 | 9.7 | 77.0 | 207.8 | 162.4 | 18.4 | 79.4 | 300 | 187.9 | 19.5 | 81.1 | 300 |
Time in center and on closed arms (s) | 168.2 | 9.5 | 111.9 | 246.4 | 201.6 | 15.6 | 104.2 | 300 | 241.2 | 15.6 | 152.6 | 300 |
Time in immobility (s) | 198.2 | 8.4 | 131.6 | 269.5 | 205.7 | 15.7 | 86.0 | 300 | 219.4 | 13.2 | 114.6 | 290.8 |
Average velocity on open arms (m/s) | 0.044 | 0.004 | 0.019 | 0.083 | 0.040 | 0.007 | 0 | 0.099 | 0.032 | 0.007 | 0 | 0.081 |
Average velocity on closed arms (m/s) | 0.074 | 0.006 | 0.032 | 0.129 | 0.070 | 0.012 | 0 | 0.148 | 0.061 | 0.011 | 0 | 0.139 |
Total distance covered (m) | 13.6 | 1.0 | 6.5 | 25.1 | 12.6 | 1.8 | 0 | 27.9 | 11.1 | 1.4 | 3.8 | 22.9 |
Number of entries open arms (n) | 4.4 | 0.6 | 0 | 11 | 4.3 | 0.8 | 0 | 10 | 2.9 | 0.7 | 0 | 9 |
Number of entries closed arms (n) | 2.9 | 0.3 | 1 | 6 | 2.4 | 0.4 | 0 | 5 | 2.1 | 0.4 | 0 | 5 |