Fig. 6From: Using in vivo oxidation status of one- and two-component redox relays to determine H2O2 levels linked to signaling and toxicityTheoretical temporal gradients of H2O2 in response to 0.1 (filled triangles) and 0.5 mM (open circles) H2O2. Gradients are estimated according to Eq. 4. P s of 0.096 ± 0.034 μm s− 1 (n = 17) was determined in this work from experiments with OxyR oxidation, giving kperm = 0.141 ± 0.051 s− 1 (n = 17). kcatabolism was estimated from the reduction levels of Tpx1 and catalase and rate constants of 1 × 107 M− 1 s− 1 and 4.6 × 107 M− 1 s− 1, respectively. When Tpx1 and catalase are 100% active in eliminating H2O2, kcatabolism = 41 s− 1, as indicated in Table 2Back to article page