The microbiome of the upper respiratory tract in health and disease

Table 2 The nasal microbiome of chronic rhinosinusitis patients

Study	Population	Sample site	Actinobacteria	Bacteroidetes	Firmicutes	Proteobacteria
Lal et al. 2017 [29]	Adults with nasal polyps	Middle meatus	Streptococcus Haemophilus Fusobacterium
Lal et al. 2017 [29]	Adults without nasal polyps	Middle meatus	Corynebacterium		Staphylococcus Alloiococcus
Copeland et al. 2018 [6]	Adults	Middle meatus	↓Corynebacterium	↑Porphyromonas ↑Prevotella	↑Anaerococcus ↑Lactobacillus ↑Finegoldia ↑Peptoniphilus ↑Dialister ↑Parvimonas ↓Staphylococcus ↓Dolosigranulum
Hoggard et al. 2018 [20]	Adults	Middle meatus	↓Corynebacterium ↓Propionibacterium		↓Anaerococcus ↓Finegoldia ↓Peptoniphilus ↓Staphylococcus
Aurora et al. 2013 [176]	Adults	Middle meatus	↑Corynebacterium ↑Curtobacteria		↑Staphylococcus	↑Pseudomonas
Cope et al. 2017 [168]	Adults	Sinus	Corynebacteriaceae		Staphylococcaceae Streptococcaceae	Pseudomonadaceae

Arrows indicate an increase (↑) or decrease (↓) in relative abundance in CRS patients compared to healthy subjects. Relative abundance was analyzed by 16S rRNA sequencing

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