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Fig. 5. | BMC Biology

Fig. 5.

From: Spatiotemporal mapping of RNA editing in the developing mouse brain using in situ sequencing reveals regional and cell-type-specific regulation

Fig. 5.

Single-cell data. Dot plots showing the correlation between observed and expected cells with both edited and unedited transcripts (mixed cells) for the developmental stages E15 in a, P0 in b, P7 in c, and adult in d. Each dot or triangle is one edited substrate, where the shape indicates the classification based on gene function (Additional file 21). The observed proportion of mixed cells is extracted from single-cell data for cells with at least one read each of the edited and the unedited substrate assigned. The expected proportion is calculated from the observed editing level, assuming a random distribution of reads. The dotted line indicates a perfect correlation and provides a point of reference for the observed under-representation of mixed cells compared to what would be expected

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