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Table 1 Descriptive statistics of the analyses sample from the Luxembourg Parkinson’s Disease Study

From: Parkinson’s disease-associated alterations of the gut microbiome predict disease-relevant changes in metabolic functions

Variable

PD

Control

Missing values

PD (%)

Control (%)

Cases vs. controls

147

162

0

0

Female subjects

31.5%

35.8%

0

0

Age at basic assessment (mean ± SD)

69.3 ± 8.6

63.3 ± 8.3

0

0

Body mass index (mean ± SD)

27.3 ± 4.5

27.9 ± 4.8

0.7

0

Sniff score (mean ± SD)

7.1 ± 3.4

12.7 ± 2.1

0

0

Diabetes

4.1%

3.1%

0

0

Non-motor symptoms questionnaire score (NMS-PD) (mean ± SD)

9.3 ± 5.1

3.9 ± 3.9

9.5

3.7

Constipation

36.7%

6.2%

0

0

PD disease duration since diagnosis

5.9 ± 5.7

6.1

UPDRS-part I (mean ± SD)

10.0 ± 5.9

4.5 ± 4.4

3.4

3.1

UPDRS-part II (mean ± SD)

11.8 ± 8.1

1.3 ± 2.8

1.4

2.4

UPDRS-part III (mean ± SD)

34.6 ± 16.1

2.3 ± 2.9

1.4

0

UPDRS-part IV (mean ± SD)

1.7 ± 3.2

1.4

Hoehn and Yahr (mean ± SD)

2.2 ± 0.6

0

L-DOPA intake

66.7%

0%

0

0

Dopamine agonist intake

56.5%

0%

0

0

MAO-B inhibitor intake

41.5%

0%

0

0

COMT inhibitor intake

4.1%

0%

0

0

  1. PD disease duration refers to the time since diagnosis at the date of stool sampling
  2. SD standard deviation, UPDRS Unified Parkinson Disease Rating Scale, L-DOPA levodopa, MAO-B monoaminooxidase B, COMT catecholamine-methyl-transferase, NMPC net maximal production capability, “–” no value to report