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Fig. 7 | BMC Biology

Fig. 7

From: Unraveling the molecular interactions involved in phase separation of glucocorticoid receptor

Fig. 7

Model of GR condensate formation. The cartoon represents the successive steps of a GR focus formation, according to the proposed model. (i) Initially, GR directly or indirectly bind certain chromatin regions. (ii) Mediator and other multivalent cofactors form an incipient interactions network with other chromatin-bound GR molecules. (iii) The focus expands by the incorporation of a growing number of molecules through a weak interactions network. Molecules dynamically exchange from and to the focus

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