Fig. 3

Phylogenomics analysis of the C. felis genome. a Assessing completeness and conservation of select holometabolan genomes using insect (n = 1658) Benchmarking Universal Single-Copy Orthologs (BUSCOs) [30]. b Multidimensional scaling plots gauging within- and across-order similarity of protein orthologous groups. Inset show the color scheme for holometabolous orders. c Upset plot illustrating C. felis protein orthologous groups that intersect with other holometabolous insects. Inclusion criteria: one protein from at least one genome/order must be present. Yellow bar, 577 proteins found in all analyzed genomes. Inset, redrawn phylogeny estimation of Holometabola [2]; numbers indicate C. felis unique protein groups or higher-generic monophyletic groups (see Additional file 5: Table S2)