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Fig. 7 | BMC Biology

Fig. 7

From: The transcriptional trajectories of pluripotency and differentiation comprise genes with antithetical architecture and repetitive-element content

Fig. 7

Tissue-specific gene signature and widely expressed genes exhibit opposite length and Alu density biases. a Classification of the GTEx cohort using the SVM model trained on the tissue-specific genes. The rows of the heatmap show the original tissue of origin and the columns the predicted tissue type. The color shade of each cell indicates the percentage of samples that were of the “original” respective tissue and were “predicted” to be the respective tissue type. The “Other” category captures samples with low prediction probability. The high percentages on the diagonal indicate the high accuracy of the model. As the SVM was run with 10-fold cross-validation, the heatmap indicates the average of 10 runs. b Exon (top) and intron (bottom) length distributions of tissue-specific and widely expressed genes. Asterisks indicate a statistically significant difference from the background distribution (P value < 10−4; Kolmogorov-Smirnov test). c Heatmap showing the enrichment and depletion in repetitive-element families of the widely expressed and tissue-specific genes

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