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Table 1 Summary of the different definitions of positive (driver variants) and negative (passenger variants) samples used in the construction of cancer driver variant predictors data sets

From: Current cancer driver variant predictors learn to recognize driver genes instead of functional variants

Negative samples

 

Positive samples

 

Neutral germline variants

NEUT

Experimentally verified cancer drivers

EXPDRV

Deleterious germline variants

DEL

Recurrent variants in cancer samples

REC

Both DEL and NEUT

ALL

  

Non-recurrent variants in cancer samples

NONREC

  

Synthetically generated passenger mutation

SYNTH

  
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BMC Biology

ISSN: 1741-7007

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