Fig. 5

Imaging of cells and tissues on biomaterial scaffolds. a Segmented 3D nCT reconstruction of human fibroblast cells (green) on a poly (lactide-co-glycolide) (PLGA) fibre scaffold (grey), reproduced with permission from [22]. b Virtual cross-section (left) alongside a 3D segmented μCT reconstruction (right) showing bone in-growth on a hydroxyapatite scaffold after 6 weeks implantation within a critical size defect of a Yucatan minipig mandible [77] Image in b reprinted from [77], Biomaterials, 28(15), van Lenthe GH, Hagenmuller H, Bohner M, Hollister SJ, Meinel L, Muller R. Nondestructive micro-computed tomography for biological imaging and quantification of scaffold-bone interaction in vivo, p.2479–90, 2007, with permission from Elsevier