Fig. 2
From: Toxic stress-specific cytoprotective responses regulate learned behavioral decisions in C. elegans
ccBA preconditioning induces behavioral and physiological stress tolerance, while ccDA preconditioning induces sensitization. a Experimental setup for preconditioning, followed by food aversion and survival tests. Animals were exposed to a hanging drop of undiluted odor (preconditioned, PC) or vehicle (naive), washed, and assayed for food avoidance or survival by exposure to the same or a lethal odor dose, respectively. b Food aversion induced by 1 μl ccBA of naive and ccBA-preconditioned (1 μl for 4 h) animals at different time points. c Food aversion induced by 4 μl of ccDA of naive and ccDA-preconditioned (4 μl for 4 h) animals at different time points. d Survival of naive and ccBA-preconditioned worms 14 h after a 3-h exposure to 8 μl ccBA. e Survival of naive and ccDA-preconditioned worms 14 h after a 3-h exposure to 16 μl ccDA. Data are expressed as mean ± SEM. N, number of independent experiments. p values were obtained by one-way ANOVA with Fisher’s LSD post hoc test. n.s., not significant; *p < 0.05; **p < 0.01; ***p < 0.001