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Fig. 3 | BMC Biology

Fig. 3

From: Assessing optimal: inequalities in codon optimization algorithms

Fig. 3

Comparison of the DNA sequences of KRas4B as a function of the relative codon profiles. a Violin plot (top) and %MinMax heat map (bottom) of the native CDS (a.a. 1–188) using the codon usage frequencies for H. sapiens or E. coli. b Violin (top) and %MinMax plots (bottom) for KRas4B CDSs (a.a. 1–169) optimized for expression in E. coli. Statistical significance was determined with a Mann-Whitney-Wilcox rank-sum test: n.s., no significance; *p < 1E−02, **p < 1E−05

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