Fig. 3
From: Single-cell alternative polyadenylation analysis delineates GABAergic neuron types
Benchmarking analysis of SAPAS on quantification of APA at single-cell level. a–c The t-SNE plots of single-cell APA profiles estimated by SAPAS (a), QAPA (b), and Dapars (c) on a benchmarking scRNA-seq dataset of PBMCs. The cell types are labeled using different colors as shown, including B cell, CD14+ monocyte, CD16+ monocyte, CD4+ monocyte, cytotoxic T cell, megakaryocyte, and natural killer cell. d–f The bar charts show the silhouette analysis of clustering results from single-cell APA profiles estimated by SAPAS (d), QAPA (e), and Dapars (f). The Y-axis represents the silhouette width, and the X-axis represents single cells ordered by corresponding silhouette width decreasingly by cell types