Fig. 2

Scaled heatmaps of surface marker expression (log2 scale) in each main cell type. A CD4+ T cells, B CD8+ T cells, C monocytes, D B cells, and E NK cells. Immunophenotypes at the bottom. Em, effector memory; Emra, terminally differentiated effector memory; Treg, regulatory T cells; Tfh, follicular helper T cells; CM, classical monocyte; INT, intermediate monocyte; NCM, nonclassical monocyte; hi, high; lo, low. To denote each of the clusters, the letter “C” is used in CD4+ T, CD8+ T, B, and NK cells followed by the cluster number. In the case of monocytes, clusters are represented as INT, CM, or NCM followed by the cluster number. Only expressed (non-negative) markers are shown