Fig. 3

Cell proportions in women with HIV, CVD, both, or neither. HIV−CVD− (green), HIV+CVD− (yellow), HIV+CVD+ (blue), and HIV+CVD+ CRT+ (red), from left to right. Eight samples per group except 7 for HIV+CVD+. Proportions of cells in each cluster calculated as percentage of the parent cell type as indicated in the title of each panel. A B cell cluster 4, B CD8+ T cell cluster 7, C INT monocyte cluster 2, and D NCM cluster 3. Clusters with significant differences (p-value) in cell proportions (calculated by log odds ratio (p/(1−p)), followed by ANOVA and Tukey’s multiple comparison test), are shown with individual points as well as means and standard error of the mean (SEM). INT, intermediate monocytes; NCM, nonclassical monocytes; CVD, cardiovascular disease; CRT, cholesterol-reducing treatment