Fig. 1
From: The microbiome’s fiber degradation profile and its relationship with the host diet
A schematic illustration of our framework. A Annotation of GH and PL enzymes, indicating the glycoside bonds each enzyme can break down. B Annotation of dietary fibers, indicating the set of glycoside bonds each enzyme includes. C A matrix representation of the links between dietary fibers and GH/PL enzymes. A red cell indicates that the enzyme in this column is capable of operating on one of the bonds included in the dietary fiber in this row. D, E Mapping of metagenomic reads to a database of GH and PL sequences, resulting in a matrix describing the abundance of each GH/PL enzyme in each sample. This profile is further referred to in our work as the functional fiber-specific profile (FFP). F The inferred fiber degradation profile (IFDP) can be obtained by multiplying the DF-enzyme matrix by the FFP