Fig. 4

Histone modifications regulate the transcriptional response to symbiosis. A Total number of symbiosis-repressed (blue) and induced (pink) genes associated with each histone modification in their gene body and promoter regions. Average peak distributions of symbiosis-repressed (blue) and induced (pink) genes associated with H3K27me3 (B), H3K36me3 (C), H3K4me3 (D), H3K27ac (E), and H3K9ac (F) from −2kb of TSS through gene body and +2kb of TES. Each of the line plots from symbiosis-repressed genes is compared with induced genes (see respective boxplots, unpaired two-tailed Student’s t test; ****p < 2.2 × 10⁻¹⁶)