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Table 1 Differentially expressed genes up-regulated in the tolerant and down-regulated in the sensitive strains. ND is no data

From: The genomic basis of copper tolerance in Drosophila is shaped by a complex interplay of regulatory and environmental factors

Gene name

Biological process

Molecular function

Prior copper response association

CG13078

ND

Heme binding, oxidoreductase activity, transmembrane ascorbate ferrireductase activity

Within QTL (Everman et al.) [20]

CG31091

Lipid metabolic process

Sterol esterase activity, triglyceride lipase activity

ND

Hml

Haemolymph coagulation, haemostasis, wound healing

Protein homodimerization activity, chitin binding

Up-regulated in control vs. treated (Everman et al.) [20]

Jon99Ci

Proteolysis

Endopeptidase activity, serine-type endopeptidase activity

ND

Lectin 24Db

ND

Fucose binding, glycosylated region protein binding, mannose binding

Down-regulated in control vs. treated (Everman et al.) [20]

NtR

Chemical synaptic transmission, ion transmembrane transport, nervous system process, regulation of membrane potential, signal transduction

Extracellular ligand-gated ion channel activity, neurotransmitter receptor activity, transmembrane signalling receptor activity

ND