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The Landscape of TREG Differentiation

A proteomic and transcriptomic profiling of human regulatory T cells identifies new regulators of their differentiation

Genome of Tiny Wasps Tells About Miniaturization

Amelia Lindsey and colleagues report the genome of the miniature parasitic wasp Trichogramma pretiosum, providing insights into its biology and applications as pest control

The Trouble With RNA Contaminants

Paul Wilmes and colleagues report that RNA isolation and purification can leave behind small RNA contaminants which can be also identified in published datasets

Caring for Parents: an Evolutionary Rationale

Eörs Szathmáry and colleagues use mathematical modeling to examine whether the cultural norm of helping aging parents can spread through Darwinian competition

Shaping Social Recognition

Jane Hurst and colleagues show that polymorphic combinatorial major urinary proteins shape the volatile odor signatures that mice use to recognize each other

Reviews in BMC Biology

Stay up to date with our authoritative Reviews from leaders in the field, on topics including the microbiome, cancer, evolution, neurobiology, cell biology and genetics

Featured Q&A

Q&A: Trash talk: disposal and remote degradation of neuronal garbage

Meghan Lee Arnold, Ilija Melentijevic, Anna Joelle Smart and Monica Driscoll

Published on: 30 January 2018

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Articles

Research
Identification of a neuronal population in the telencephalon essential for fear conditioning in zebrafish
Pradeep Lal, Hideyuki Tanabe, Maximiliano L. Suster, Deepak Ailani, Yuri Kotani, Akira Muto, Mari Itoh, Miki Iwasaki, Hironori Wada, Emre Yaksi and Koichi Kawakami
Published on: 25 April 2018

Research
Madagascar ground gecko genome analysis characterizes asymmetric fates of duplicated genes
Yuichiro Hara, Miki Takeuchi†, Yuka Kageyama, Kaori Tatsumi, Masahiko Hibi, Hiroshi Kiyonari and Shigehiro Kuraku
Published on: 16 April 2018

Research
A phylogenomic framework and timescale for comparative studies of tunicates
Frédéric Delsuc, Hervé Philippe, Georgia Tsagkogeorga, Paul Simion, Marie-Ka Tilak, Xavier Turon, Susanna López-Legentil, Jacques Piette, Patrick Lemaire and Emmanuel J. P. Douzery
Published on: 13 April 2018

Research
Genomics analysis of Aphanomyces spp. identifies a new class of oomycete effector associated with host adaptation
Elodie Gaulin, Michiel J. C. Pel, Laurent Camborde, Hélène San-Clemente, Sarah Courbier, Marie-Alexane Dupouy, Juliette Lengellé, Marine Veyssiere, Aurélie Le Ru, Frédéric Grandjean, Richard Cordaux, Bouziane Moumen, Clément Gilbert, Liliana M. Cano, Jean-Marc Aury, Julie Guy, Patrick Wincker, Olivier Bouchez, Christophe Klopp and Bernard Dumas
Published on: 18 April 2018

Methodology
Cell fixation and preservation for droplet-based single-cell transcriptomics
Jonathan Alles, Nikos Karaiskos, Samantha D. Praktiknjo, Stefanie Grosswendt, Philipp Wahle, Pierre-Louis Ruffault, Salah Ayoub, Luisa Schreyer, Anastasiya Boltengagen, Carmen Birchmeier, Robert Zinzen, Christine Kocks and Nikolaus Rajewsky
Published on: 19 May 2017

Forum
Non-model model organisms
James J. Russell, Julie A. TheriotEmail author, Pranidhi Sood, Wallace F. MarshallEmail author, Laura F. Landweber, Lillian Fritz-Laylin, Jessica K. Polka, Snezhana Oliferenko, Therese Gerbich, Amy Gladfelter, James Umen, Magdalena Bezanilla, Madeline A. Lancaster, Shuonan He, Matthew C. Gibson, Bob Goldstein, Elly M. Tanaka, Chi-Kuo Hu and Anne Brunet
Published on: 29 June 2017

Review
The biological function of the cellular prion protein: an update
Marie-Angela Wulf, Assunta Senatore and Adriano Aguzzi
Published on: 2 May 2017

Review
Meta-evaluation of meta-analysis: ten appraisal questions for biologists
Shinichi Nakagawa, Daniel W. A. Noble, Alistair M. Senior and Malgorzata Lagisz
Published on: 3 March 2017

Commentary
Phylogenomics resolves the evolutionary chronicle of our squirting closest relatives
Gonzalo Giribet
Published on: 27 April 2018

Q&A
Q&A: How do gene regulatory networks control environmental responses in plants?
Ying Sun and José R. Dinneny
Published on: 11 April 2018

  1. Content type: Research article

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    Authors: Winfried Schlee, Nadia Mueller, Thomas Hartmann, Julian Keil, Isabel Lorenz and Nathan Weisz

  2. Content type: Forum

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    Authors: Wallace F Marshall, Kevin D Young, Matthew Swaffer, Elizabeth Wood, Paul Nurse, Akatsuki Kimura, Joseph Frankel, John Wallingford, Virginia Walbot, Xian Qu and Adrienne HK Roeder

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Aims and scope

BMC Biology is a broad scope journal covering all areas of biology. Our content includes research articles, new methods and tools. BMC Biology also publishes reviews, Q&A, and commentaries.

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