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Fifteen Years of BMC Biology

To mark our fifteen-year anniversary, in this special collection we bring together pieces from a selection of the authors, reviewers, and editorial board members who have been part of our journey, sharing their stories and perspectives

A New Cyclops Emerges from Algae

Armin Hallmann, Georg Nagel and colleagues report a novel opsin family from green algae, showing that these light-inhibited guanylyl cyclases are regulated through a two-component-like phosphoryl transfer, naming them “two-component cyclase opsins” (2c-Cyclops)

Bacterial Proteins in Evolving Mitochondria

Pavel Dolezal and colleagues map mitochondrial TAT translocases in diverse eukaryotic lineages and determine how these bacterial-derived proteins contribute to protein transport during mitochondrial evolution

Respiratory Chain Supercomplexes

Our EBM Judy Hirst discusses the functional and structural features of the supramolecular assemblies of respiratory enzymes known as supercomplexes, and the advantages they may confer to mitochondrial respiration

Call for Papers – "Microbiome Biology"

BMC Biology and Genome Biology are inviting submission for our upcoming joint special issue on microbiome biology scheduled for publication in Spring 2019

Call for Papers – special issue on Cancer Metabolism

We are now inviting submissions of Research papers for our cross-journal special issue. Guest Editors: Navdeep Chandel, Matthew Vander Heiden, Karen Vousden and Kathryn Wellen. Read more here!

Featured Q&A

Q&A: Array tomography

Stephen J Smith

Published on: 6 September 2018


Comparison of village dog and wolf genomes highlights the role of the neural crest in dog domestication
Amanda L. Pendleton, Feichen Shen, Angela M. Taravella, Sarah Emery, Krishna R. Veeramah, Adam R. Boyko and Jeffrey M. Kidd
Published on: 28 June 2018

Ontogenetic and phylogenetic simplification during white stripe evolution in clownfishes
Pauline Salis, Natacha Roux, Olivier Soulat, David Lecchini, Vincent Laudet and Bruno Frédérich
Published on: 05 September 2018

Nuclear genome sequence of the plastid-lacking cryptomonad Goniomonas avonlea provides insights into the evolution of secondary plastids
Ugo Cenci, Shannon J. Sibbald, Bruce A. Curtis, Ryoma Kamikawa, Laura Eme, Daniel Moog, Bernard Henrissat, Eric Maréchal, Malika Chabi, Christophe Djemiel, Andrew J. Roger, Eunsoo Kim and John M. Archibald
Published on: 28 November 2018

Evolution of mitochondrial TAT translocases illustrates the loss of bacterial protein transport machines in mitochondria
Markéta Petrů, Jeremy Wideman, Kristoffer Moore, Felicity Alcock, Tracy Palmer and Pavel Doležal
Published on: 22 November 2018

Common ancestry of heterodimerizing TALE homeobox transcription factors across Metazoa and Archaeplastida
Sunjoo Joo, Ming Hsiu Wang, Gary Lui, Jenny Lee, Andrew Barnas, Eunsoo Kim, Sebastian Sudek, Alexandra Z. Worden and Jae-Hyeok Lee
Published on: 5 November 2018

Open Questions
Open questions: CRISPR biology
Eugene V. Koonin
Published on: 24 September 2018

From plant immunity to food security: an interview with Ksenia Krasileva
Ksenia Krasileva
Published on: 1 November 2018

Studying the microbiome and its complexities: an interview with Alan Walker
Alan Walker
Published on: 1 November 2018

Open Questions
Open questions: why are babies rarely born with cancer?
Michelle Monje
Published on: 1 November 2018

When a physicist wanders into biology…: an interview with KC Huang
Kerwyn Casey Huang
Published on: 1 November 2018

  1. Content type: Research article


    Authors: Winfried Schlee, Nadia Mueller, Thomas Hartmann, Julian Keil, Isabel Lorenz and Nathan Weisz

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Focus: Genome Editing

Read the latest Reviews on genome editing across BMC flagship journals.

Genome editing for inborn errors of metabolism: advancing towards the clinic
Jessica L. Schneller, Ciaran M. Lee, Gang Bao and Charles P. Venditti
Published in BMC Medicine on: 27 February 2017

Structural insights into the inactivation of CRISPR-Cas systems by diverse anti-CRISPR proteins
Yuwei Zhu, Fan Zhang and Zhiwei Huang
Published in BMC Biology on: 19 March 2018

Resources for the design of CRISPR gene editing experiments
Daniel B. Graham and David E. Root
Published in Genome Biology on: 27 November 2015

Key challenges in bringing CRISPR-mediated somatic cell therapy into the clinic
Dianne Nicol, Lisa Eckstein, Michael Morrison, Jacob S. Sherkow, Margaret Otlowski, Tess Whitton, Tania Bubela, Kathryn P. Burdon, Don Chalmers, Sarah Chan, Jac Charlesworth, Christine Critchley, Merlin Crossley, Sheryl de Lacey, Joanne L. Dickinson, Alex W. Hewitt, Joanne Kamens, Kazuto Kato, Erika Kleiderman, Satoshi Kodama, John Liddicoat, David A. Mackey, Ainsley J. Newson, Jane Nielsen, Jennifer K. Wagner and Rebekah E. McWhirter
Published in Genome Medicine on: 25 September 2017

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