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Figure 1 | BMC Biology

Figure 1

From: The eggshell is required for meiotic fidelity, polar-body extrusion and polarization of the C. elegansembryo

Figure 1

Hexosamine pathway for biosynthesis of UDP-GlcNAc and UDP-GalNAc. Fructose 6-phosphate enters glycolysis by conversion to fructose 1,6-diphosphate, catalyzed by 6-phosphofructokinase, or enters the hexosamine pathway by conversion to glucosamine 6-phosphate, catalyzed by glucosamine-fructose 6-phosphate aminotransferase (GFAT). Two enzymes required for UDP-GlcNAc synthesis (glutamine synthetase-5 (GLN-5)) and glucosamine 6-phosphate N-acetyltransferase-2 (GNA-2)) are targets of GLD-1 translational repression in C. elegans (shown by a gold oval encompassing the mRNA). C. elegans homologues are in brackets; those underlined are oogenesis enriched [56] and have an osmotically-sensitive embryonic lethal phenotype by RNAi [20]; this study.

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BMC Biology

ISSN: 1741-7007

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