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Table 7 Differences in phospholipids associated with connexin junctional plaques.

From: Connexin channels and phospholipids: association and modulation

Plaque

Headgroup

Linkage

Carbon atoms (number)

Saturation

Cx26

PC, PE, PA, PI, PS. Approx. 50% anionic.

More ether-linkages than unique to Cx32.

Range 28 to 44. Mean 39. Median 40.

Broad distribution.

Cx32

PC, PE, PA, PI, PS. More anionic than Cx26.

Fewer ether-linkages than unique to Cx26.

Range 22 to 38. Mean 31. Median 32.

Broad distribution, shorter chains more saturated.

Cx26 and Cx32

PC, PE, PA. No unique species of PI and PS. Predominantly zwitterionic.

Fewer ether-linkages than unique to Cx26, similar to Cx32.

Range 30 to 38. Mean 35. Median 36.

Broad distribution, shorter chains more saturated.

  1. Abbreviations as previously.