Figure 2

Influence of 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate (CHAPS) for ligand-receptor interaction. Binding affinities of the ligands bone morphogenic protein (BMP)2, BMP7 and growth and differentiation factor (GDF)5 to the immobilized type I receptors BMP receptor (BMPR)-IA and BMPR-IB (a) and those of the same ligands plus activin A to the type II receptors activin receptor (ActR)-II, ActR-IIB, and BMPR-II (b) are depicted as bar diagrams. The data represent mean values of two individual experiments using six different ligand concentrations. Standard deviations are indicated by error bars.